Pre-seed & seed VC, US
SOSV
Venture capital firm · Princeton · Founded 1995
Quick read
SOSV is a pre-seed and multi-stage deep tech VC, founded in 1995 and headquartered in Princeton, NJ. It's the world's most active deep tech pre-seed firm, deploying capital through accelerator programs HAX (hardware), IndieBio (life sciences), and the recently independent Orbit Startups. As of 2026, SOSV manages $1.5B in AUM across a portfolio of 800 active companies valued at $18.2B.
Key facts
- Founded
- 1995
- Founders
- Sean O'Sullivan
- Employees
- 68
- Sectors
- hardware, biotech, climate, ai, healthcare
- Website
- sosv.com
Investment thesis
SOSV backs deep tech founders at pre-seed, writing first checks into life sciences, hardware, and climate companies through its accelerator programs (HAX for hardware, IndieBio for life sciences). The firm then follows on through seed and later rounds, aiming to build companies with measurable impact on human and planetary health.
Recent activity
- Apr 2026investmentSOSV participated in Fermeate's $2M seed round for optogenetics-based fermentation control. tracxn.com
- Mar 2026investmentSOSV joined a $6M seed extension round in Surf Therapeutics. startupintros.com
- Jan 2026pressPortfolio company Particle was acquired by Digi International. tracxn.com
- Jan 2026pressSOSV published its 2026 portfolio snapshot: 800 active companies had raised $7.3B and were valued at $18.2B, anchored by its $306M SOSV V fund. sosv.com
- 2025leadershipSean O'Sullivan announced IndieBio's evolution within SOSV, rebranding the SF and NY programs under unified SOSV branding with Po Bronson leading as General Partner. linkedin.com
- 2025investmentSOSV co-invested in Logos Research, an Imperial College London spinout building AI code reliability tools, alongside Khosla Ventures and XTX Ventures. linkedin.com
- 2025investmentSOSV co-invested in unspun, a carbon-reduction apparel company that closed $57M with DCVC and Lowercarbon Capital. sosv.com
- 2025pressPo Bronson, General Partner, published SOSV's climate hard tech trend outlook for 2026. linkedin.com
Notable investments
- Surf TherapeuticsSeed Extension ($6M)Mar 2026startupintros.com
- FermeateSeed ($2M)Apr 2026tracxn.com
- unspunGrowth ($57M)2025sosv.com
- Logos ResearchSeed2025linkedin.com
- The EVERY CompanySeries D ($55M)n/azoominfo.com
Key people
Named individuals at the firm. We don't expose direct email or phone — use their LinkedIn for outreach.
- Sean O'Sullivan · Founder & Managing Director
- Po Bronson · General Partner (SF & NY)
- Parikshit Sharma · Partner, IndieBio
Sources
Other VCs in United States
- Sequoia Capital · Generalist VC, Menlo Park·
- Andreessen Horowitz · Generalist VC, Menlo Park·
- Benchmark Capital · Early-stage VC, San Francisco·
- Founders Fund · Contrarian VC, San Francisco·
- Khosla Ventures · Multi-stage VC, Menlo Park·
- Greylock Partners · Early-stage VC, Menlo Park
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Frequently asked
What is SOSV?+
SOSV is a pre-seed and multi-stage deep tech VC, founded in 1995 and headquartered in Princeton, NJ. It's the world's most active deep tech pre-seed firm, deploying capital through accelerator programs HAX (hardware), IndieBio (life sciences), and the recently independent Orbit Startups.
Where is SOSV headquartered?+
SOSV is headquartered in Princeton, United States.
When was SOSV founded?+
SOSV was founded in 1995 by Sean O'Sullivan.
What sectors does SOSV invest in?+
SOSV focuses on hardware, biotech, climate, ai, healthcare. They primarily invest in these sectors.
How do I prepare for a meeting with SOSV?+
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Try Brief →Generated by briefthecall.com from public web sources. Last updated June 5, 2026. Each claim is linked to its source above.
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