Pre-seed & seed VC, US
SOSV
Venture capital firm · Princeton · Founded 1995
Quick read
SOSV is a pre-seed and multi-stage deep tech VC, founded in 1995 and headquartered in Princeton, NJ. It's the world's most active deep tech pre-seed firm, deploying capital through accelerator programs HAX (hardware), IndieBio (life sciences), and the recently independent Orbit Startups. As of 2026, SOSV manages $1.5B in AUM across a portfolio of 800 active companies valued at $18.2B.
Key facts
- Founded
- 1995
- Founders
- Sean O'Sullivan
- Employees
- 68
- Sectors
- hardware, biotech, climate, ai, healthcare
- Website
- sosv.com
Investment thesis
SOSV backs deep tech founders at pre-seed, writing first checks into life sciences, hardware, and climate companies through its accelerator programs (HAX for hardware, IndieBio for life sciences). The firm then follows on through seed and later rounds, aiming to build companies with measurable impact on human and planetary health.
Recent activity
- Aug 2026investmentPrinceton Critical Minerals raised $16M to scale lithium production for energy storage, covered by Axios. sosv.com
- Aug 2026pressSOSV announced HAX Plasma Forge's new home at Princeton's SRI, continuing its commitment to invest in 25+ plasma-related startups over five years. sosv.com
- Aug 2026pressSOSV will participate in Climate Week NYC 2026, scheduled for the week of August 17. sosv.com
- May 2026pressSOSV announced the Deep Tech Summit, coming November 4–6, focused on climate tech, human health, and AI for the physical world. sosv.com
- Jul 2026productSOSV hosted its 2026 VC-Founder Therapeutics Matchup online July 13–17, drawing 571 founders and investors who generated over 1,000 meetings. SOSV has now invested in 10 startups sourced through its matchup events. sosv.com
- Mar 2026pressIndieBio New York held an Investor Showcase on March 11, 2026. sosv.com
- Mar 2026investmentSOSV participated in a $6M Seed Extension round for Surf Therapeutics. startupintros.com
- Early 2026productSOSV rebranded IndieBio San Francisco and IndieBio New York as SOSV SF and SOSV NY, reflecting the firm's broader deep tech identity beyond biotech. sosv.com
- Jul 2026pressSOSV announced the Deep Tech Summit coming November 4–6, covering climate tech, human health, and AI for the physical world. sosv.com
- Jul 2026investmentSOSV hosted the 2026 VC-Founder Therapeutics Matchup (July 13–17), connecting 250+ startups with 250+ investors in 1:1 online meetings. SOSV has now closed 10 investments sourced directly from past matchups. sosv.com
- May 2026pressSOSV ran the 2026 VC-Founder Physical AI Matchup (May 11–15), a virtual event pairing 250+ startups with 250+ investors. The 2025 matchup series generated over 6,500 one-on-one meetings across health tech and related categories. sosv.com
- Apr 2026fundraiseSOSV confirmed $1.5B AUM anchored by the $306M SOSV V fund. At the start of 2026, its 800 active portfolio companies had raised $7.3B and were valued at $18.2B. sosv.com
Notable investments
- Princeton Critical Mineralsundisclosed ($16M)Aug 2026sosv.com
- Surf TherapeuticsSeed Extension ($6M)Mar 2026startupintros.com
- TippingPoint BiosciencesSeed ($4.5M)2026zoominfo.com
- FermeateSeedApr 2026sosv.com
- CauldronSeries A2026zoominfo.com
- AlunaSeries B2025leadiq.com
- FermeateSeed ($2M)Apr 2026sosv.com
- Logos ResearchSeedJan 2026linkedin.com
- CauldronSeries A ($13.25M additional)Jan 2026zoominfo.com
- unspunGrowth ($57M)2025sosv.com
- The EVERY CompanySeries D ($55M)n/azoominfo.com
Key people
Named individuals at the firm. We don't expose direct email or phone — use their LinkedIn for outreach.
- Sean O'Sullivan · Founder & Managing Director
- Po Bronson · General Partner (SF & NY)
- Parikshit Sharma · Partner, IndieBio
Sources
- About SOSV
- SOSV Homepage
- SOSV Investor Profile – Tracxn
- SOSV – Startup Intros
- SOSV LinkedIn
- SOSV – OpenVC
- https://sosv.com/news/
- https://sosv.com/events/
- https://sosv.com/press/
- https://www.linkedin.com/in/parikshit-sharma-indiebio/
- https://www.zoominfo.com/c/sosv-llc/369730518
- https://sosv.com/news/?_company_trends=climate-tech-100
- https://sosv.com/announcing-sosvs-vc-founder-therapeutics-matchup-july-13-17/
- https://hax.co/sosv-innovation-day-2026/
- https://sosv.com/announcing-indiebio-new-york-investor-showcase-march-11-2026/
- https://sosv.com/news/?_company_trends=sosv-consortium
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Frequently asked
What is SOSV?+
SOSV is a pre-seed and multi-stage deep tech VC, founded in 1995 and headquartered in Princeton, NJ. It's the world's most active deep tech pre-seed firm, deploying capital through accelerator programs HAX (hardware), IndieBio (life sciences), and the recently independent Orbit Startups.
Where is SOSV headquartered?+
SOSV is headquartered in Princeton, United States.
When was SOSV founded?+
SOSV was founded in 1995 by Sean O'Sullivan.
What sectors does SOSV invest in?+
SOSV focuses on hardware, biotech, climate, ai, healthcare. They primarily invest in these sectors.
How do I prepare for a meeting with SOSV?+
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